Posted on by

Tirzepatide

Brief Description

Tirzepatide is a novel dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. It has shown significant potential in treating type 2 diabetes and obesity by enhancing insulin secretion, slowing gastric emptying, and promoting satiety.

Use Case

Tirzepatide is primarily used to manage blood glucose levels in adults with type 2 diabetes. Its dual action on GIP and GLP-1 receptors helps in better glycemic control and substantial weight loss, making it a promising treatment for individuals with obesity or metabolic syndrome.

Reconstitution

To reconstitute Tirzepatide:

  1. Use sterile water or bacteriostatic water.
  2. Add the appropriate amount of water to the vial containing the Tirzepatide powder. Typically, this is 1mL of water for every 10mg of peptide.
  3. Gently swirl the vial until the powder is fully dissolved. Do not shake vigorously to avoid denaturing the peptide.
  4. Use the Calculators section on our website to create custom reconstitution and dosing plans tailored to your needs.

Dosing

The typical dosing regimen for Tirzepatide varies based on the individual’s needs and response:

  • Starting Dose: 2.5 mg once weekly.
  • Maintenance Dose: Increase to 5 mg, 10 mg, or 15 mg once weekly based on the individual’s tolerance and therapeutic response.
  • Max Dose: 15 mg once weekly.

Cycles:
Tirzepatide is generally used on a continuous weekly dosing schedule without specific cycles. However, it is crucial to follow your healthcare provider’s guidance regarding duration and adjustments.

Side Effects

Common side effects of Tirzepatide may include:

  • Nausea
  • Diarrhea
  • Vomiting
  • Constipation
  • Decreased appetite
  • Injection site reactions

Severe but less common side effects can include pancreatitis and severe gastrointestinal problems. Users should monitor for signs of these conditions and consult with a healthcare provider if severe symptoms occur.

Sources of Information